Question: How Effective Is Methotrexate For Ectopic Pregnancy?

How long does methotrexate take to work for ectopic?

When this happens, we know that the medication has worked. This can take at least 4-6 weeks.

What is the success rate of methotrexate?

According to the statistics in the literature, the success rate of MTX treatment varies from 65 to 95%, with a mean rate of 82%, and the fertility rate with delivery after medical treatment for ectopic pregnancy is 67–80.7%, which is not less than that after conservative and radical surgery [4,5,6,7], [8,9,10,11,12].

What happens to ectopic pregnancy after methotrexate?

The methotrexate will stop the pregnancy and the level of pregnancy hormone in your blood should decrease over 2 to 4 days. Based on your blood test results, your doctor will tell you if you need another injection of methotrexate.

What happens if methotrexate doesn’t work for ectopic pregnancy?

If methotrexate therapy doesn’t work, surgery is the next step. It’s also the only option for women with high hCG levels, severe symptoms, and ruptured or damaged fallopian tubes. You may have laparoscopic surgery that involves a very small cut and a tiny camera.

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How soon after methotrexate will I start bleeding?

A few days after the injection, it is usual to begin to bleed and this bleeding can last between a few days and up to 6 weeks. It is usual to have some discomfort and pain initially but as long as this is not severe.

How soon after methotrexate will I get my period?

Most find that their period arrives sometime around week six or seven after surgery, or, if treated without surgery, at some time in the four weeks after their hCG levels have fallen to below 100 mIU/mL. Before you can have a period, you would usually have to ovulate.

How fast do hCG levels drop after methotrexate?

If single-dose therapy is used, serum hCG concentrations are measured on the day of administration and on days 4 and 7 after administration. hCG levels frequently increase between the day of administration and day 4; however, there should be a 15% or greater drop in hCG between days 4 and 7.

Can tube still rupture after methotrexate?

There is still around a one in 14 chance of your fallopian tubes splitting open (rupture) after medical treatment with methotrexate, even if your hCG levels are going down. Therefore, be aware of the potential symptoms of a rupture and be ready to call an ambulance if you think a rupture has occurred.

Can methotrexate make you infertile?

Methotrexate may cause an increased chance of infertility, not birth defects. Low sperm count has been seen in some men using methotrexate. Most of these men were using high doses of the medication, as well as other medications to treat cancer. Sperm levels returned to normal after the men stopped taking methotrexate.

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What should I avoid after methotrexate for ectopic pregnancy?

Yes, during treatment with methotrexate you should avoid the following:

  • Heavy exercise.
  • Sexual intercourse.
  • Alcohol.
  • Vitamins and foods that contain folic acid, including fortified cereal, enriched bread and pasta, peanuts, dark green leafy vegetables, orange juice, and beans.

How long stop folic acid after methotrexate?

Avoid taking these medicines during methotrexate treatment and for one week after your treatment has finished. Products containing folic acid, including multivitamins, can reduce the effectiveness of treatment with methotrexate.

Has any baby survived an ectopic pregnancy?

Doctors have hailed as a “miracle” the birth of a baby who beat odds of 60m to one to become the first to develop outside the womb and live. Not only did the baby boy and his mother survive an ectopic pregnancy – but so did two other baby girls. Ronan Ingram was one of three children born to Jane Ingram, 32.

Can an ectopic rupture after methotrexate?

Patient(s): Eighty-one women diagnosed with an ectopic gestation treated with MTX: 19 patients experienced subsequent tubal rupture, and 62 patients experienced ectopic resolution.

How long can an ectopic pregnancy last before it ruptures?

The structure containing the fetus typically ruptures after about 6 to 16 weeks, long before the fetus is able to live on its own. When an ectopic pregnancy ruptures, bleeding may be severe and even threaten the life of the woman.

How long does pain last after methotrexate for ectopic pregnancy?

About two to seven days after the injection you will probably have some pain in your lower abdomen. It should not be severe and lasts four to 12 hours. You can also expect to have vaginal bleeding which is light or like a period. This lasts a few days but you may have a brown discharge for two to three weeks.

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